14-year-old girl reported missing after she doesn't come home from school; Kidnapping survivor recalls life in captivity and how she kept hope alive.

Interview with Elizabeth Thomas, who was taken at age 15 by her Tennessee high school teacher, resulting in a 38-day nationwide manhunt.

Stories of Americans who followed their dreams and started new careers later in life, including a woman who quit her finance job to pursue acting, and a woman who became the oldest person to graduate the from the Houston Police Academy.

Audio detailing the night Prince nearly died from overdose on plane; Prince suddenly dies at Paisley Park from fentanyl overdose.

Teacher's gruesome 1992 death launches decades-long mystery; Pennsylvania teacher's 1992 death grows cold

An exclusive sit-down interview with first lady Melania Trump.

11-year-old arrested for his pregnant soon-to-be stepmother's murder: Why police believe ex-boyfriend was not connected to woman's murder; What it's like to be 11 years old and accused of murder

A $3.5 million mansion, a beautiful family's future up in flames; Closing in on the brutal killer in DC mansion murders; Friends, family testify against suspect at trial for DC mansion murders

Former hockey star's young family shattered by wife's murder at home; Manhunt begins for brutal killer of mother of two; 7-year-old daughter becomes key eyewitness in attack on mom.

From Michelle Obama's humble Chicago upbringing to the White House; Michelle Obama opens up about miscarriage, IVF and marriage counseling

26-year-old face transplant recipient: 'I see me'; Face transplant recipient's mom learns about renowned reconstructive surgeon

How the idea for 'Mary Poppins Returns' was born; 'Mary Poppins Returns' star Emily Blunt on making the role her own

A daughter fights for justice after her mother was allegedly killed in husband's murder-for-hire plot.

Texas couple's wedding anniversary celebration ends in tragedy; Woman discovered tied up in a closet, husband stabbed, beaten to death; Woman's family believes husband's killer is still out there

Looking back at the legacy of a president.

Chris and Shanann Watts' seemed to be in love, say friends, family; In a shocking statement, Chris Watts describes how he killed his wife; Shanann Watts and her two daughters are found dead.

Gypsy Rose Blanchard opens up about why she plotted to kill her mother and explains what life was like with her; Nicholas Godejohn, Gypsy's ex-boyfriend, alleges that Gypsy was the mastermind behind the murder and he was a hired hit man.

A look back at the notorious Bobbitt case from 1993 with an exclusive new interview with John Wayne Bobbitt.

In a case that remains shrouded in mystery, actor Robert Blake speaks to "20/20" thirteen years after he was acquitted in his wife's murder.

Jim and Tammy Faye Bakker were among the most famous televangelists in America when their religious empire came crashing down amid sex and financial fraud scandals.

Steven and Cary Stayner: The tale of two brothers' horror and heroism.

After "BTK" serial killer Dennis Rader's shocking confession, his daughter had to find ways to cope with her new, shattered reality.

When Stacey Castor's second husband dies suddenly, investigators learn her first husband is also dead. Castor is suspected of murdering her second husband and poisoning her own daughter.

During the 1970s, the notorious serial killer had murdered dozens of women on a rampage that took him across the Pacific Northwest and eventually to Florida.

A former Uber driver terrorizes the city of Kalamazoo, Mich., on Feb. 20, 2016, killing six people and seriously injuring two others.

When 19-year-old Sarah Stern's car is mysteriously found on a New Jersey bridge, a former classmate comes forward with information that helps authorities discover what happened.

Dr. Joseph Sonnier met his girlfriend Richelle Shetina at a dance class, and the two traveled to Paris together, just weeks before the unthinkable happened.

The Dropout The story of Elizabeth Holmes and the fall of her start-up Theranos is an unbelievable tale of ambition and fame gone terribly wrong.

A woman shoots her three young children, seriously injuring two and killing one.

The two beautiful young Mormon athletes seemed to have a perfect marriage, but Janet's sisters say that changed dramatically when Abaroa revealed he cheated

a 21-year-old Miami hotel guest has no memory of being attacked, raped and left for dead.

Actress Rebecca Schaeffer is shot point blank at the door of her Los Angeles home by her longtime stalker;

A woman who believed she was conceived by an anonymous sperm donor discovers her biological father is actually her mother's former fertility doctor.

A mother on death row for the unthinkable. Now the court orders testing on crucial crime scene evidence.

A man convicted of murder has his conviction overturned by an appeals court and waits to see if a higher court agrees it should be overturned.

Revisiting the 1989 case of a female jogger who was brutally raped and beaten in New York City.

Daniel Wozniak was a community theater actor in California when he was arrested for the murders of Sam Herr, a war veteran, and Julie Kibuishi, a college student and dancer, in May 2010.

When a woman is found unresponsive in her bathtub, two of her daughters suspect their father is responsible.

Trump on polls showing Biden ahead: 'I don't believe those polls; Trump on Mueller, immigration and putting his personal touch on Oval Office.

How did an ordinary-looking American family turn into pistol-wielding bank robbers?

When a woman secretly records her husband's affair, she snaps and kills his girlfriend and herself.

A lifelong hustler discovers the strip club scene; Strip club workers' new hustle takes a dark turn; Doctor almost swindled out of $100,000 after three dates with woman.

Detectives use DNA evidence to solve a cold case involving the murder of an 18-year-old woman.