Grissom and crew are called in after high roller Tony Braun, a known drug addict, is found dead in his house by a gardener. Since drug paraphernalia is discovered near his body and it is also determined that he had recently inhaled heroin, the cause of death is at first thought to be an overdose. But further examination of the corpse reveals that Braun had been restrained at some point with duct tape, leading Grissom to believe that the victim was forced to ingest lethal amounts of heroin and, perhaps, other drugs.

The entire CSI team investigates a disappearance at a local university. A young woman vanished, seemingly off the face of the earth.

Grissom investigates a possible suicide at a high-profile construction site. Catherine takes on a case with a teenage boy who dies while in session with his female psychologist,

When the class clown at the local high school is found murdered, the CSI team is called to investigate, while Nick and Sara respond to the crime scene of a decomposed body found in a bag.

Grissom, Sara and Warrick are called on to investigate an abandoned, blood-splattered apartment and Nick and Catherine must examine a dead scuba diver lodged in a tree.

Grissom and his team investigate a murder suspect who is caught red-handed -- burying the victims -- while Catherine and Warrick take on the case of a woman found dead in a hotel spa.

Grissom and Nick investigate the death of a book restorer while Catherine and Sara are called to the scene of a fatal train crash.

Grissom and Catherine investigate the apparent violent death of a woman found in a sandbox. Warrick and Sara are called to a crime scene to investigate a shooting, which initially appears to have taken place during a robbery.

Grissom and his team investigate a casino heist during which innocent victims were shot, while Catherine and Sara are called to the scene of a murder in a remote part of the desert.

Warrick heads the investigation of the murder of a con artist who turns out to be involved with Brass' daughter, and the evidence leads Sara on a counterfeit investigation.

When the body of Bob Fairmont, the real estate developer, is found, the team discovers that the crime scene has been tampered with and that the victim has been re-dressed.

Grissom and Sara are called to the crime scene when two murder victims are found hidden in pipes at a construction site in the middle of an alfalfa field, while Catherine and Nick investigate an ostensible hunting accident.

Grissom's nemesis, serial killer Paul Millander, reappears and claims a third victim in this gripping episode. The latest slaying matches Millander's previous killings in that it recreates his father's murder. The killer's next target was born Aug. 17, 1956...which just happens to be Grissom's birthday.

Catherine is ordered by a kidnapper to accompany a man who is to deliver $1 million in ransom to him or else he will kill the man's mistress.

Grissom investigates the murder of a Las Vegas photographer whose remains were dumped at a nearby body farm where CSIs routinely study corpses, and his findings reveal that the man was apparently shot to death even though there are no bullet fragments in the body.

Grissom, Catherine and Sara are called in to investigate the death of a hockey player on the ice. Warrick and Nick look into the apparent drug-related death of a sax player at a casino.

Grissom investigates the murders of four monks who were shot point blank while chanting in a Buddhist temple; Catherine reopens a cold case in which her best friend was murdered, after the man convicted of the crime claims he's innocent shortly before he dies.

A bus carrying 23 passengers from Los Angeles to Las Vegas crashes less than 40 miles from its destination, killing nine people. Tthe CSIs soon discover that a recent parolee was on the bus, but is now unaccounted for.

Jane Galloway lives in fear. Her doors are triple-locked. Every shade is drawn. The bathroom window is nailed shut. An alarm system is activated. Who killed Jane, and how could the murderer have possibly entered, and left, the house?

Grissom and Catherine investigate the stabbing death of an 80-year-old woman who lived in a run-down house full of cats; Nick and Sara comb through the remains of a car bombing that was, apparently, a murder plot gone awry.

Grissom and Sara investigate when a man's body, which has been doused with lye, is found buried in a park; Nick tries to determine how a hiker apparently drowned in a desert.

Grissom and his crew handle their highest profile case to date when the city's former chief of detectives is slain execution-style in his house following a wild party. Missing from the residence are the chief's trophy wife and their 7-year-old daughter. Catherine and Warrick follow the trail to Miami, and soon enlist the help of Horatio Caine.