The honeymoon is over for Mike and Sully as the newlyweds must adjust to life in a changing Colorado Springs where a bullish Boston Brahman named Preston A. Lodge III establishes the towns first bank. Preston Lodge III: Jason Leland Adams.

The town invites a traveling all-star baseball team for a fundraising event, but later suspects that they have been swindled. Otis James: Joel Anderson.

Mike is overwhelmed with her new found passion for Sully, and feeling slighted, Colleen joins her schoolmates for dangerous and questionable escapades.

Matthew's fiance Ingrid hovers near death after being bitten by Brian's rabid pet wolf; Brian is overwhelmed with guilt. Ingrid: Jennifer Youngs.

An elderly man comes to town with hopes that the natural spring will help his rheumatism. Dr. Mike can't convince Sully to plan for the Halloween festivities.

Dorothy Jennings' book about her experiences in Colorado Springs becomes a best seller, but it angers townsfolk.

Loren proposes to Dorothy but suffers a stroke before she can give him an answer. Meanwhile, Sully feels obliged to act upon an old friend's written request to help him set up a mining operation in Nevada.

Dr. Mike celebrates her birthday by climbing Pikes Peak with Dorothy, Grace and Myra, but ends up injured and alone when her companions turn back.

Dorothy, Myra and Grace realize they are quitting and they're letting Mike down, so they decide to go back. They find her injured with a broken arm. Mike can't go to the top of the mountain anymore, but she encourages the others to make it to the top for her. Meanwhile back in town, Preston plots to guild a hotel-casino with help from his ""partner"" Jake; and Robert E is bothered by an encounter with a bounty hunter.

At Thanksgiving, Mike faces the possibility that she might be infertile, while Jake struggles with the fact that he has no family to share the day with. Brian becomes attached to the Thanksgiving main course.

The family finds Matthew running a saloon at a railroad camp where his grief over Ingrid's death drives him to volunteer for a dangerous blasting job. Loren loses Dorothy's money for a new printing press. Peter Chow: Eric Michael Zee.

As Colorado Springs prepares for Christmas, the family receives a rambunctious toy poodle from Mike's mother in Boston, and Brian has a case of puppy love for a new girl in town. The Rev. Johnson recruits folk for a Nativity pageant. Sara Sheehan: Jann Michaels. Mrs. Sheehan: Susanna Thompson.

Robert E and Grace want to adopt a young boy who is suffering from a disease Mike can't diagnose (sickle cell anemia). Meanwhile the town believes Matthew should start dating again and sets him up on a series of blind dates.

Increasing lawlessness in Colorado Springs sparks a demand for a new sheriff, and Matthew feels he's just the man for the job. Meanwhile, Brian succumbs to peer pressure shoplifting a toy train from Loren's store. Zachary Brett: Travis Tritt. Charles: John Christian Graas.

Matthew falls for an independent young woman, but the fact that she's a prostitute complicates their blooming romance. Meanwhile, Preston offers Myra a job at the bank, but Horace opposes her taking it. Emma: Charlotte Chatton.

The town is duped by two con men selling shares in a refrigeration box and Mike must turn the tables on the con men, helping the town learn a lesson in trust. Meanwhile, Cloud Dancing barters with Loren to sell corn grown on the reservation at the general store. Randolph Cummings: Brandon Douglas. Curtis Roper: Anthony Lee. Anthony: Brenden Jefferson.

Sully pursues a renegade mountain man who has kidnapped senator Leonard's son, in protest of the Senator's support of Colorado statehood. Meanwhile, Mike is forced to stop her practice when her schedule threatens her pregnancy. Ezra Leonard: Lawrence Pressman. Noah McBride: Denny Miller. Dr. Cassidy: Jerry Hardin.

The rescuers get ugly after Leonard offers a bounty for the mountain man, so Sully sets off alone.

The Reverend mortgages the church to Hank to get money to make church repairs in order to impress his mentor Rev. Thomas. Rev. Thomas: Fred Rogers. Mr. James: Max Gail.

Cloud Dancing sees a reservation school as fatal to Indian culture; bankers stonewall Dorothy's loan request.

Dr. Mike's joyful reunion with a college friend soon turns competitive; Dorothy struggles with a new press.

Tales of her accomplishments embarrass Woman of the Year nominee Mike; Hank's grandmother visits.

A renegade stabs Cloud Dancing, and Emma has a tumor, so Mike cannot slow down before the baby is born.

A popular new arrival carries a dread disease; Preston plans an exclusive clinic.

Cloud Dancing hopes his trial for shooting a soldier will unite the tribes.

Dr. Mike prepares for the birth of her baby. Mike's family arrives for the impending birth of Mike and Sully's baby, bringing along a new young doctor (Brandon Douglas) to help deliver the baby. Meanwhile, Sully is hurt while trying to rescue Cloud Dancing and others from Sgt. O'Connor (Patrick Kilpatrick) and his patrol.

Wounded Sully must deliver Mike's baby. Dr. Cook is forced to perform a major operation. Katie Sully: Alexandria, McKenzie and Megan Calabrese.