Dave makes an unusual offer to Moammar Khadafi; throughout the night, Dock Diving Dogs make a splash out on 53rd Street; Howie Mandel explains the origins of his obsessive-compulsive disorder; The Dirty Projectors performed "Cannibal Resource."

A message from the Department of Labor; a staffer gives Dave a 16th anniversary t-shirt (courtesy of Dave); Jeremy Piven puts the mercury poisoning rumors to rest; Rumor Willis plugs Sorority Row; The Black Crowes performed "Good Morning, Captain."

Billy Crystal and John Fogerty are the scheduled guests.

Footage of Dick Cheney wheezing through an interview on Fox News; Dave expresses jealousy towards Neil Patrick Harris for appearing on the cover of the CBS/Viacom magazine "Watch!" and asks him about his recent trip onboard the Orient Express; Steve Mazan riffs on hotel keycards; Dave shows a doctored "Watch!" magazine with him on the cover; Edward Sharpe & The Magnetic Zeros performed "Home."

Tony Blair and Julianna Margulies are the scheduled guests.

Barack Obama becomes the first president to appear on the Late Show while in office. During his 30+ minute sit-down with Dave, President Obama discusses the economy, foreign policy, and health care reform. Quote Dave: "Your job is more difficult than my job."

Larry David, Olivia Wilde and Tom Russell are the scheduled guests.

CBS Orchestra bandleader Paul Shaffer, Eliza Dushku and KISS are the scheduled guests.

Tom Hanks and Weezer are the scheduled guests.

Al Gore and Brad Paisley are the scheduled guests. Plus, a special Top Ten from Michael Buble!

Ricky Gervais, Brian Regan, and Ralph Stanley are the scheduled guests.

Dave rambles on about an pre-show audience question that really wasn't; a Top Ten list with no theme; Kate Walsh looks back at the early days of her acting career; Andre Agassi promotes his autobiography and "retires" his mullet wig; Norah Jones performed "Chasing Pirates."

Dave briefly comments on the overusage of the word "douche"; Sharon Stone talks about her kids and defends her decision to pose topless in Paris Match; Seth Meyers shares a funny story about a goat; Wyclef Jean and Cyndi Lauper performed "Slumdog Millionaire."

Stephen Colbert, Emily Blunt, and John Mayer are the scheduled guests.

Hugh Grant, Zoe Saldana, and Alicia Keys are the scheduled guests.

Maggie Gyllenhaal and John Witherspoon are the scheduled guests. Plus, a Top Ten list from Stewie Griffin!

Susan Sarandon and Colbie Caillat are the scheduled guests. Plus, "Top Ten Christmas Carols!"

Alec Baldwin gets intimidated by an acting legend. Also: Jay Thomas returns and Darlene Love sings "Christmas (Baby Please Come Home).

Michael Cera, Jenna Elfman, and David Gray are the scheduled guests.

Did "Chuck" star Zachary Levy almost get a guy killed? Plus: Amy Adams and music from Vampire Weekend.

Dave & Sigourney Weaver turn "Avatar" blue. Plus: Marv Albert's wild & wacky sports bloopers and Julian Casablancas performs.

Bradley Cooper, Rachel Maddow, and Nick Jonas are the scheduled guests. Plus, the "Top Ten Things I've Learned From the Last 20 Years of Television," presented by Homer Simpson.

Teri Hatcher strips with broken ribs. Plus: comedian Jake Johannsen and the music of The Dodos.

Whoopi Goldberg, Jason Sudeikis, Findlay Brown.

Why is Kiefer Sutherland wearing a dress? Also tonight: those NBC pinheads, Keri Russell & music from The HotRats.

Was Dave fondled on the operating table? Celebrate the 10th anniversary of his heart surgery with Dr. O. Wayne Isom. Plus Denzel Washington: Bad Heart Surgeon, and music from The Low Anthem.

Tonight: an incredible week comes to an end with Glenn Close, comedian Eddie Brill and music by Matt Morris.

Tonight: Kristen Bell, Randy Jackson and The Heavy. Dave responds to NBC's Dick Ebersol, plus what will "The Tonight Show" look like in the year 2042?

Dwayne "The Rock" Johnson, Bettina Luescher, and The Swell Season are the scheduled guests.

Harrison Ford, Lou Reed and the Blind Boys of Alabama

Actor Bruce Willis; Ne-Yo performs.

Actor John Travolta; snowboarder Shaun White; Ben Harper and Relentless7 perform.

Comic Sarah Silverman; actor Jeremy Renner; Paris Hilton presents the Top Ten list; Nneka performs.

Actor Jamie Foxx; actress Amanda Seyfried; Robin Thicke performs.

Animal handler Jack Hanna; comic Joe Wong; the Swell Season performs.

Drew Brees, Sandra Bullock, and Josh Turner are the scheduled guests. Plus, the cover of the 2010 Sports Illustrated swimsuit issue is unveiled!

Jennifer Garner; the 2010 Sports Illustrated cover model; Sade; ``Survivor'' contestants.

Jessica Biel; Christoph Waltz; Josh Turner; ``Survivor'' contestants.

Regis and Joy Philbin; Elizabeth Banks; Benicio Del Toro.

Actor Jeff Bridges; comic Joe Wong; the Soft Pack performs.

Actor Tracy Morgan; the winner of the Daytona 500; Fanfarlo performs.

Stupid Pet Tricks; actor Ben Kingsley; Mary J. Blige performs.

Actor Ewan McGregor; comic Abby Elliott; Mumford & Sons perform.

Actress Scarlett Johansson; Daniel Merriweather performs.

TV personality Nicole Richie; comic Tom Papa.

Actor Bill Murray; Ludacris performs.

Author Mitt Romney; actress Mia Wasikowska; figure skater Evan Lysacek presents the Top Ten list.

Comic Jerry Seinfeld; journalist Tom Brokaw.

Actor Tom Hanks, Spoon, and a Top Ten list presented by US Winter Olympic Bobsled Gold Medalists Steve Holcomb, Justin Olsen, Steve Mesler, and Curt Tomasevicz.

Actor Matt Damon; comic Danny Bhoy; Corinne Bailey Rae performs.

TV host Kelly Ripa; Lady Antebellum performs.

Actress Julianna Margulies; grocery bagging champion Kyle Perry; Broken Bells perform.

Jessica Simpson; Mehmet Oz; Rod Blagojevich; Alkaline Trio.

Real estate mogul Donald Trump.

Actor Liev Schreiber; comic Jim Gaffigan; Drive-By Truckers perform.

Actress Jennifer Aniston; environmentalist Charles Moore.

TV host Jimmy Kimmel; actress Kirstie Alley; rapper Snoop Dogg presents the Top Ten list.

Actor Ben Stiller; chef Jamie Oliver; Justin Bieber performs.

Actress Tina Fey; actor Bryan Cranston; Joan Jett and the Blackhearts perform.

Actor Robin Williams; eliminated ``American Idol'' contestant Paige Miles; Usher performs.

Actor Luke Wilson; President of the Sandpoint Tea Party Patriots Pam Stout; Alan Jackson performs.

Actor Ricky Gervais; turkey callers; The Whigs perform.

Actor Sam Worthington; sportscasters Mike Greenberg and Mike Golic; Patty Loveless performs.

Actor Nathan Lane; She & Him perform.

Singer Courtney Love; actor Michael Caine; Hole performs.

Actor Robert Downey Jr. (Iron Man 2); OK Go performs.

Actress Gwyneth Paltrow (Iron Man 2); a performance by the Broadway cast of ``American Idiot.''

Professional soccer player David Beckham; comic Mike Birbiglia; the Hold Steady performs.

Actor Mickey Rourke (Iron Man 2); actor Jim Parsons (The Big Bang Theory); eliminated ``American Idol'' contestant Siobhan Magnus.

Actor Russell Crowe (Robin Hood); Sharon Jones and the Dap-Kings (CD, "I Learned the Hard Way") perform.

Animal handler Jack Hanna; actress Kerry Washington; Willie Nelson performs.

Journalist Brian Williams; author Beth Ostrosky Stern; Court Yard Hounds perform.

Actress Amanda Peet (Please Give); comic Nick Griffin; Wale (CD, "Attention Deficit") performs.

Actress Evangeline Lilly; actor Sam Rockwell; eliminated ``American Idol'' contestant Aaron Kelly; a performance by the Broadway cast of ``Million Dollar Quartet.''

Actress Queen Latifah; actor Will Forte; MGMT performs; Oakland Athletics pitcher Dallas Braden presents the Top Ten List.

Actor Michael Keaton; actress Jenna Fischer.

Actor Alec Baldwin; the National performs.

Actor Mike Myers; comic Tom Dreesen.

Matthew Fox; Zac Brown Band; Jason Randal; Michael Lynche.

Jonah Hill; Janelle Monáe; John Carney; Miss USA Rima Fakih presents the Top Ten list.

Russell Brand; Johnny Ace Palmer; Stone Temple Pilots; Damon Lindelof and Carlton Cuse.

Actress Katherine Heigl; magician Steve Cohen; Band of Horses performs.

Ashton Kutcher; Larry Miller; Brooks & Dunn; Michael Ammar; Reba McEntire.

Actress Miley Cyrus, TV personality Rick Harrison.

Actress Jada Pinkett Smith; comic Larry Miller; Fred Eaglesmith performs.

Actress Salma Hayek (Grown Ups), Chris "Mad Dog" Russo

Regis Philbin (Daytime Emmy Awards), Trombone Shorty & Orleans Avenue (CD, "Backatown")

Actor Adam Sandler( Grown Ups); Bettye LaVette (CD, "Interpretations: The British Rock Songbook") performs.

Actor Kevin James (Grown Ups), journalist Thomas L. Friedman (Book, "Hot, Flat, and Crowded 2.0: Why We Need a Green Revolution--and How It Can Renew America")

Jay-Z (CD, "The Blueprint 3"), Top Ten with Eminem, Jay-Z and Eminem (CD, "Recovery")

Guests include actress Kristen Stewart (The Twilight Saga: Eclipse), Gary Faulkner (Guy who tried to hunt down Osama bin Laden), with musical geust Tokyo Police Club (CD, "Champ") and a Top Ten with John Isner (Winner of the Longest Tennis Match in History)

Singer Dolly Parton (Hallmark's Dolly Celebrates 25 Years of Dollywood), Landon Donovan (USA National Soccer Team).

Actress Julianne Moore (The Kids Are All Right); astronaut Mike Massimino; The New Pornographers perform (CD, "Together").

Actor Taylor Lautner (The Twilight Saga: Eclipse); director Barry Sonnenfeld.

Actor Nicolas Cage (The Sorcerer's Apprentice); Steel Train (CD, "Steel Train") performs.

Actress Kristin Chenoweth (Broadway's "Promises, Promises"); journalist Jonathan Alter (Book, "The Promise: President Obama, Year One"); M.I.A. (CD, "Maya") performs.

Summer toy demonstration; actor Joseph Gordon-Levitt (Inception); Laurie Anderson (CD, "Homeland") performs.

Actress Kyra Sedgwick (The Closer); singer Bret Michaels (CD, "Custom Built"); Jimmy Cliff (CD, "Existence") performs.

Actor Sylvester Stallone; actor Rob Corddry; Robyn performs.

Actor Steve Carell; actress Selena Gomez; Sheryl Crow performs.

Actor Bill Murray; Alejandro Escovedo performs.

Comic Joan Rivers; comic Bill Burr; Steve Winwood performs.

Actor Denis Leary; MLB player Albert Pujols; Jimmy Webb performs.

Actor Luke Wilson; actress Kristen Schaal; Dierks Bentley performs.

Actor Michael Keaton; The Flaming Lips perform.

Actor Paul Rudd; comic Bill Burr; Interpol performs.

Actor Will Ferrell (The Other Guys); Nas and Damian Marley (CD , "Distant Relatives") perform.

Actor Michael Cera (Scott Pilgrim vs. The World); TV show host Rachel Maddow (The Rachel Maddow Show); Herbie Hancock (CD, "The Imagine Project") performs.

Actress Julia Roberts (Eat, Pray, Love); The Dead Weather (CD, "Sea of Cowards") performs.

Actor Mark Wahlberg (The Other Guys); Dock Diving Dogs; comedian Cory Kahaney; VV Brown (CD, "Traveling Like The Light") performs.

Actress Drew Berrymore; Katy Perry performs.

Dave welcomes actress Christina Applegate, comedian Tom Dreesen and The Pretty Reckless performs.

Dave welcomes actress Anne Heche, documentarian Ken Burns and The Specials perform.

Dave welcomes actress Jessica Alba, comic Jimmie Walker and Ryan Bingham & The Dead Horses.