1. Luke Wilson, Julie Chen, Lee Brice

2. Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers

3. Steve Buscemi, Indy Car Season Champ, Alt-J

4. Tina Fey, Moody McCarthy, Kevin Drew

5. Bill Maher, Henrik Lundqvist, Spoon

6. Michael Strahan, Richard Branson, Interpol

7. Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson

8. Jason Bateman, Billy Eichner, Ryan Adams

9. Mindy Kaling, Jake Johannsen, Maddie & Tae

10. Mark Harmon, "Jungle" Jack Hanna

11. Denzel Washington, Lenny Kravitz

12. Kelly Ripa, Jim Gaffigan, Paloma Faith

13. Jerry Seinfeld, Michael Jackson ONE

14. Ted Danson, Andrew Norelli

15. Neil Patrick Harris, Jamie Oliver, Aretha Franklin

16. John Oliver, Maggie Q, Bleachers

17. Bill O'Reilly, Cristin Milioti

18. Johnny Galecki, Andre Benjamin, Delta Spirit

19. Mariska Hargitay, Simon Amstell, Kandace Springs

20. Aziz Ansari, Tom Dreesen

21. Robert Downey Jr., Sarah Paulson, Lizzo

22. Anderson Cooper, Gina Rodriguez, Hatsune Miku

23. Robert Duvall, Elle Fanning, Rival Sons

24. Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley

TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs.

25. Russell Brand, Dave Grohl, Foo Fighters

26. Michael Keaton, Foo Fighters

27. Bill Murray, Foo Fighters

28. Tom Selleck, Jenny Slate, Foo Fighters

29. Jessica Chastain, Lenny Marcus, Foo Fighters

30. Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis

31. Taylor Swift, Tom Mison

32. Jim Carrey, David Tennant

33. Brian Williams, Perfume Genius

34. Keith Olbermann, Brian Regan, Run the Jewels

35. Martin Short, Father John Misty

36. Jennifer Lopez, Rob Riggle, Kimbra

37. Whoopi Goldberg, Jimmy Page, Mapei

38. Amy Schumer, Jeff Caldwell

39. Katie Holmes, Alex Zanardi

40. Steve Carell, Martha Stewart, OK Go

41. Jennifer Lawrence, Boris Johnson

42. Jon Stewart, Shawn Mendes

43. Kristin Chenoweth; Chris Young

Actress Kristin Chenoweth; Chris Young performs.

44. Jason Sudeikis, Allison Janney, Damien Rice

45. Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger

46. Regis Philbin, Hundred Waters

47. Edward Norton, Jessye Norman

48. Norman Lear, TV on the Radio

49. Seth Rogen, Amy Sedaris

50. Emily Blunt, Adam Resnick, Wu-Tang Clan

51. Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz

52. Joaquin Phoenix, Cristela Alonzo, Al Green

53. Ben Stiller, Olivia Munn, LaLa Brooks

54. Meryl Streep, Rebel Wilson, J. Cole

55. Chris Rock, Sting

56. Jamie Foxx, Robert Klein, Dan Penn

57. Emma Stone Top, Marcus Mariota, Bob Seger

58. New Holiday Toys, Anna Kendrick, Charli XCX

59. Tom Brokaw, Will Nelson & Billy Joe Shaver

60. Rosie O’Donnel,l Jeff Altman

61. Jay Thomas, Josh Brolin, Darlene Love

The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home).

62. Kathy Griffin, David Oyelowo, Lera Lynn

63. Ethan Hawke, Allison Williams, Parquet Courts

64. Julianne Moore, Catfish & the Bottlemen

65. Donald Trump, Chelsea Peretti, Foxygen

66. Michael Somerville, Nicole Atkins

67. Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones

68. Anderson Cooper, Shovels & Rope

69. Amanda Peet, Ryn Weaver

70. Larry David, Dan Patrick, Sleater-Kinney

71. Urban Meyer, Johnny Beehner, Ella Henderson

72. Louis CK, Nicolle Wallace, the Lone Bellow

73. Andrew Luck, Oscar Isaac, Drenge

74. Viola Davis, Ben Schwartz, Marty Stuart

75. John Oliver, Mayim Bialik, Death Cab for Cutie

76. Aziz Ansari, Brian Kiley, Ben Howard

77. Jack Hanna, Sharon Jones and the Dap-Kings

78. Dr. Phil McGraw, Robin Tunney, Diana Krall

79. Ryan Reynolds, Dierks Bentley

80. Martin Short, Bettye Lavette

81. Sienna Miller, Andy Kindler, Bob Mould

82. Steve Carell, Dr. Cornel West

83. Courtney Love, Chris Elliott, Rhiannon Giddens

84. Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear

85. Tom Hanks, Sturgill Simpson

86. Bill Hader, Pat McGann, Shakey Graves

87. Matthew Perry, Adam Scott, Kishi Bashi

88. Dakota Johnson, David Tochinskiy, Twin Shadow

89. Will Smith, Grizfolk

90. Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko

91. Kid Scientists, Sean Hayes, Judah & the Lion

92. Helen Mirren, the 2015 Daytona 500 winner, Steve Earle

93. Matthew Broderick, Ellie Kemper, JD McPherson

94. Julianna Margulies, Eric Ripert, Glass Animals

95. Kevin Spacey, Lily James, Alabama Shakes

96. Patricia Arquette, Will Butler

97. Kelsey Grammer, Stevie Wonder

98. Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew

99. Kevin Bacon, Jimmie Walker, Airborne Toxic Event

100. Shailene Woodley, Dr. Cornel West, Matthew E. White

101. Will Ferrell, Glen Hansard

102. Norm MacDonald, Theo James

103. Ben Stiller, Tove Lo

104. Bill O'Reilly, Aubrey Plaza

105. James Franco, Jake Johannsen, Action Bronson

106. Neil Patrick Harris, Charlie Cox, the Suffers

107. David Duchovny, Josh Gad, Houndmouth

108. Sen. Al Franken, Billy Eichner, David Sanborn

109. Kelly Ripa, Aasif Mandvi, Fat White Family

110. Mike Myers, Nick Griffin, Banks

111. Sarah Jessica Parker, Julie Chen, Asleep at the Wheel

112. Billy Crystal, Chris Russo, Chris Stapleton

113. Michael J. Fox, Iron & Wine, Ben Bridwell

114. Kevin James, Tom Dreesen, Tracy Chapman

115. Alec Baldwin, John Mayer

116. John Travolta, Amy Schumer, the Waterboys

117. Piedmont Bird Callers, Paul Rudd

118. Bruce Willis, Dawes

119. Robert Downey Jr., Chris Russo, Elvis Costello

120. Jerry Seinfeld, Jason Isbell & Amanda Shires

121. Scarlett Johansson, John Mellencamp, Todd Rundgren

122. Michael Keaton, Future Islands

123. Jack Hanna, John Popper

124. First Lady Michelle Obama Hootie and the Blowfish

125. Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor

126. President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile

127. Reese Witherspoon, Nathan Lane, Mumford & Sons

128. Martin Short, Norah Jones

129. Tina Fey, First Aid Kit

130. Ray Romano, Brian Regan, Dave Matthews Band

131. Howard Stern, Don Rickles

132. Bill Clinton, Adam Sandler

133. Julia Roberts, Paul Shaffer, Ryan Adams

134. Al Pacino, George Clooney, Tom Waits

135. Oprah Winfrey, Norm Macdonald

136. Tom Hanks, Eddie Vedder

137. Bill Murray, Bob Dylan

138. The Final Late Show with David Letterman

6,028th broadcast

149. Episode 149

The final episode includes surprises, memorable highlights and the last Top Ten List.

Late Show with David Letterman — Season 22, Episode 21: Robert Downey Jr., Sarah Paulson, Lizzo

6.5

1993

22 Seasons

Watch Late Show with David Letterman Season 22, Episode 21: Robert Downey Jr., Sarah Paulson, Lizzo online on FlixGems. David Letterman uses mature humor to appeal to his audience in this weeknight series, which gets its music from a house band led by Paul Shaffer. Among the show's most-famous segments are the Top Ten List and Stupid Pet Tricks, the latter of which subsequently led to an additional recurring segment called Stupid Human Tricks.

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