On 16 February 2000, Emery Worldwide Flight 17 crashes into an automobile salvage yard shortly after taking off from Sacramento Mather Airport on a flight to Dayton, Ohio, killing all 3 crew members on board.

On 23 July 2014, TransAsia Airways Flight 222 crashes into buildings while attempting to land at Magong Airport during inclement weather and low visibility, killing 48 of the 58 people on board.

On 31 August 1988, Delta Air Lines Flight 1141 crashes beyond the runway while taking off from Dallas/Fort Worth International Airport, killing 14 of the 108 people on board.

On 17 July 2014, Malaysia Airlines Flight 17 disintegrates in mid-air and crashes while en route from Amsterdam to Kuala Lumpur, killing all 283 passengers and 15 crew members on board.

On 9 May 2012, an aircraft on a demonstration tour crashes into Mount Salak in the province of West Java. All 45 people on board are killed.

On 31 October 2014, an experimental spaceflight test vehicle named VSS Enterprise suffers a catastrophic in-flight breakup and crashes into the Mojave Desert in California, United States, while performing a test flight. The co-pilot, Michael Alsbury, is killed; the pilot, Peter Siebold, is seriously injured.

On 7 October 2008, Qantas Flight 72 suffers a pair of sudden uncommanded pitch-down manoeuvres during a flight from Singapore Changi Airport to Perth Airport. 119 of the 315 people on board are injured. The aircraft makes an emergency landing at Learmonth Airport near Exmouth, Western Australia.

On 14 November 1990, Alitalia Flight 404 descends too low and crashes into the woodlands of the Stalderberg Mountain near Weiach, Switzerland, 5.2 nautical miles (9.6 kilometres) short of the runway during final approach to Zurich Airport. All 46 passengers and crew members on board are killed.

On 15 November 1987, Continental Airlines Flight 1713 stalls and crashes off the right side of the runway shortly after taking off in a snowstorm from Stapleton International Airport in Denver, Colorado, on a scheduled flight to Boise, Idaho, killing 28 of the 82 people on board.