The first episode tells the story of the meteor shower that hit Smallville and changed life in the Kansas town forever. Clark Kent meets Lex Luthor for the first time and encounters the first in a long line of humans mutated by the strange green meteor rocks that accompanied him on his journey to Earth.

Clark must deal with Greg, a nerdish bug collector with a crush on Lana who gains the ability of various insects and uses them to lash out at anyone who opposes him.

An abusive and hot-tempered football coach gains the ability to control and project fire.

Clark begins experiencing "vision problems" as his x-ray vision begins manifesting. Meanwhile a mysterious shapeshifter is going about town using his or her abilities to steal and get others in trouble.

A jock named Sean gains the ability to absorb heat from everything and everyone around him, and begins preying on people to gain the heat he needs to survive.

An old man uses green meteor rock to reverse the aging process, then gain vengeance on the children of the jury that put him away decades earlier. Meanwhile, another woman at the same old folks' home has prophetic abilities and she sees the futures of both Clark and Lex.

A weight-obsessed teen dieting on kryptonite-infected vegetables gains her fondest dream...but must feed on the fat of others to maintain her enhanced appearance.

An experiment at the Luthor fertilizer plant makes an old friend of the Kents literally shake and jitter, and he seeks vengeance against the Luthors, who hide the secret of his transformation behind "Level Three" at the local plant.

Clark visits Metropolis, and does a secret good deed - a police detective witnesses this and decides to look into it.

Lex and Victoria are victims of a suspected household poltergeist. As the disturbances become more violent, suspicion lands on Amy, the daughter of a house servant who is obsessed with Lex. Not is all as it seems...

A guy in charge of a rival fertilizer firm to LuthorCorp's arrives in Metropolis. He is intent on buying up the Kent farm and using the land to build a rival company to Lex's. Clark befriends a local recluse with secrets of his own.

Whitney falls in with some former jocks who have kryptonite tattoos that give them the power to walk through walls. Meanwhile, Chloe is seriously injured and Lex has his own plans.

A man from Lex's past stalks him in conjunction with a mysterious death at Club Zero that Lex may have been responsible for. Meanwhile Chloe looks into Clark's past as an adopted child.

A flower that comes from a reopened "Level Three" of the fertilizer plant brings strange reactions from several people, including Jonathan, Lana, and Pete.

A young runaway, Ryan, has the power to read minds and flees his abusive stepparents. The Kents take him in and Clark soon discovers the boy's powers and that he's immune to them. But Ryan's stepparents have plans to use the boy's powers for financial gain against...Lex.

Tyler gains the power to destroy organic matter with a touch, and resolves to put the dying out of their misery...and Whitney's father is his next target. Meanwhile Lionel and Lex spar over Lionel's rising success in Smallville.

Clark gets into a class election and one of his opponents is a krypto-mutant who can control bees. Meanwhile a reporter from Metropolis visits to do a story on Lex.

Former Smallville High cartoonist Justin returns to Smallville after he loses the use of his hands in a hit and run accident. Meanwhile, Lex's former nanny, Pamela, comes back to see how he's doing and to apologize for leaving him after his mother's death, bringing up some old issues for Lex.

After an explosion Lana finds herself getting visions of a serial killer...and his next target is Chloe. Meanwhile Lex and Roger look further into the meteor shower and determine that something besides meteors hit Smallville that day.

Lex is hit with a surprise by his father. Clark prepares for his date with Chloe, but Mother Nature has other plans.